Table 1. Clinicopathological characteristics and univariate analysis of variables associated with inguinal lymph node metastasis.
| Total | Without metastasis | With metastasis | HR(95%CI) | P-value | |
|---|---|---|---|---|---|
| N | 110 | 69 | 41 | ||
| Age(years)(Mean+SD) | 61.6 ± 11.8 | 61.0 ± 12.0 | 62.5 ± 11.5 | 0.1 (-0.3, 0.5) | 0.529 |
| HBP(N,%) | 0.0 (-0.4, 0.4) | 0.984 | |||
| no | 94 (85.5%) | 59 (85.5%) | 35 (85.4%) | ||
| yes | 16 (14.5%) | 10 (14.5%) | 6 (14.6%) | ||
| Diabetes(N,%) | 0.1 (-0.3, 0.4) | 0.799 | |||
| no | 101 (91.8%) | 63 (91.3%) | 38 (92.7%) | ||
| yes | 9 (8.2%) | 6 (8.7%) | 3 (7.3%) | ||
| CDV(N,%) | 0.1 (-0.2, 0.5) | 0.439 | |||
| no | 102 (92.7%) | 65 (94.2%) | 37 (90.2%) | ||
| yes | 8 (7.3%) | 4 (5.8%) | 4 (9.8%) | ||
| Phimosis(N,%) | 0.2 (-0.2, 0.6) | 0.347 | |||
| no | 58 (52.7%) | 34 (49.3%) | 24 (58.5%) | ||
| yes | 52 (47.3%) | 35 (50.7%) | 17 (41.5%) | ||
| Onset_time(month) (N,%) | 0.1 (-0.2, 0.5) | 0.475 | |||
| <12 | 76 (69.1%) | 46 (66.7%) | 30 (73.2%) | ||
| >=12 | 34 (30.9%) | 23 (33.3%) | 11 (26.8%) | ||
| Number_ILN(N,%) | 0.2 (-0.2, 0.6) | 0.254 | |||
| ≥3 | 46 (41.8%) | 26 (37.7%) | 20 (48.8%) | ||
| >3 | 64 (58.2%) | 43 (62.3%) | 21 (51.2%) | ||
| Maxium_ILN(N,%) | 0.4 (0.0, 0.8) | 0.045 | |||
| >1.5cm | 72 (65.5%) | 50 (72.5%) | 22 (53.7%) | ||
| ≥1.5cm | 38 (34.5%) | 19 (27.5%) | 19 (46.3%) | ||
| T_stage(N,%) | 0.5 (0.1, 0.9) | 0.01 | |||
| Ta/T1 | 44 (40.0%) | 34 (49.3%) | 10 (24.4%) | ||
| T2 and higher | 66 (60.0%) | 35 (50.7%) | 31 (75.6%) | ||
| Differentiation(N,%) | 0.6 (0.2, 1.0) | 0.005 | |||
| lower-middle | 70 (63.6%) | 37 (53.6%) | 33 (80.5%) | ||
| higher | 40 (36.4%) | 32 (46.4%) | 8 (19.5%) | ||
| Cornification(N,%) | 0.0 (-0.3, 0.4) | 0.807 | |||
| no | 74 (67.3%) | 47 (68.1%) | 27 (65.9%) | ||
| yes | 36 (32.7%) | 22 (31.9%) | 14 (34.1%) | ||
| LVI(N,%) | 0.4 (0.0, 0.8) | 0.025 | |||
| no | 96 (87.3%) | 64 (92.8%) | 32 (78.0%) | ||
| yes | 14 (12.7%) | 5 (7.2%) | 9 (22.0%) | ||
| Nerve_infiltration(N,%) | 0.2 (-0.2, 0.6) | 0.362 | |||
| no | 92 (83.6%) | 56 (81.2%) | 36 (87.8%) | ||
| yes | 18 (16.4%) | 13 (18.8%) | 5 (12.2%) |
The P value is written in italics when it is less than 0.05
HBP, high blood pressure; CDV, cardiovascular disease; ILN, inguinal lymph node; LVI, lymphatic vascular infiltration, T stage, the TNM system of penile cancer updated in 2018; degree of tumor differentiation: According to the percentage of undifferentiated cells, the tumor was divided into middle and low differentiated groups and highly differentiated groups. CI, confidence interval; HR, hazard ratio.