Study	Reason for exclusion
Agertoft 2004	Not a parallel‐group study
Antoniu 2003	No daily ICS in 1 of the intervention groups (control group)
Apold 1975	Not a randomised controlled trial
Asrilant 1975	Not a randomised controlled trial
Bateman 2008	Participants aged ≥ 18 years
Baxter‐Jones 1998	Other group did not evaluate an additional ICS dose using the same molecule
Berger 2005	Enrolled participants were children younger than 1 year of age
Bernstein 1999	Other group did not evaluate an additional ICS dose using the same molecule
Birkebaek 1995	Not a parallel‐group study
Breborowicz 2005	Not a randomised controlled trial
Brook 1998	Not a randomised controlled trial
Brown 1973	Not a randomised controlled trial
Chuchalin 2008	Participants aged ≥ 18 years
Dickson 1973	Not a randomised controlled trial
Ferguson 2002	Other group did not evaluate an additional ICS dose using the same molecule
Godfrey 1973	Not a randomised controlled trial
Godfrey 1974	Not a randomised controlled trial
Guarnaccia 1996	Not a randomised controlled trial
Guo 2002	Not a parallel‐group study
Gwynn 1977	Not a randomised controlled trial
Hansel 2006	Participants aged ≥ 18 years
Kaiser 2008	Other group did not evaluate an additional ICS dose using the same molecule
Karpel 2007	Co‐intervention was not equivalent between comparison groups and/or was not stable throughout the observation period
Kemp 2004	Participants aged ≥ 18 years
Lang 2013	No daily ICS in 1 of the intervention groups
Laursen 1986	Participants aged ≥ 18 years
Lipworth 1996	Not a parallel‐group study
Lovera 1975	Not a randomised controlled trial
McAllen 1974	Not a parallel‐group study
Neffen 2006	Duplicate study
Nelson 2000	Co‐intervention not equivalent between comparison groups and/or not stable throughout the observation period
Niu 1998	Treatment administered for < 12 weeks
Otsuki 2009	No daily ICS in 1 of the intervention groups (control group)
Pearlman 2005	Not a randomised controlled trial
Pedeersen 2003	Not a parallel‐group study
Pedersen 2002	Other group did not evaluate an additional ICS dose using the same molecule
Peroni 2005	Co‐intervention not equivalent between comparison groups and/or not stable throughout the observation period
Phipatanakul 2003	No daily ICS in 1 of the intervention groups (control group)
Pines 1973	Not a randomised controlled trial
Skoner 2000	No daily ICS in 1 of the intervention groups (control group)
Skoner 2006	Duplication of already published paper
Skoner 2010	Treatment administered for < 12 weeks
Szefler 2008	No daily ICS in 1 of the intervention groups (control group)
Thompson 1998	Treatment administered for < 12 weeks
Turpeinen 2008	No daily ICS in 1 of the intervention groups (control group)
Visser 2001	No daily ICS in 1 of the intervention groups (control group)
Visser 2001a	Duplication of already published paper
Visser 2004	No daily ICS in 1 of the intervention groups (control group)
Wasserman 1996	Participants aged ≥ 18 years
Wasserman 1996 b	Participants aged ≥ 18 years
Waugh 2002	Not a randomised controlled trial
Williams 2010	No daily ICS in 1 of the intervention groups (control group)
Wolthers 1995	Not a parallel‐group study
Xu 2005	No daily ICS in 1 of the intervention groups (control group)