Table 2.

Interaction relationships${}^{\ast }$ between core TFs and non-core that appear in the top 25 TFs as ranked by DL $\times$ JTK${}^{†}$

S. cerevisiae			M. musculus			A. thaliana
Gene	Targeted	Targets	Gene	Targeted	Targets	Gene	Targeted	Targets
ASG1	FHL1	NDD1	EGR1	ARNTL [15]	ARNTL [16]	EPR1	RVE4	PRR5
EDS1	FHL1	TOS4	KLF10	ARNTL [17]	ARNTL [18]	PIF4	CCA1	LHY
GAT1	ACE2	ACE2	NFIC	HLF [19]		PIL6	CCA1	LHY
MTH1	FHL1	STB1	ATF5	CLOCK [20]		ARF11	CHE
RME1	ACE2	ASH1	ESR1	CLOCK [21]		CO	CCA1
RPI1	FHL1	NDD1	SREBF1		BHLHE40 [22]	COL1	CHE
SIP4	FHL1	STB1			BHLHE41 [22]	COL9	CHE
TEC1	SWI4	ASH1				MYBL2	CHE
WTM2	ACE2	STB1				CDF2		LHY
ASF1	SWI4					RVE1		PRR5
HST3	FKH1					RVE2		CCA1
HST4	MBP1
POG1	MCM1
RLF2	MBP1
RTT107	MCM1
SNF5	ACE2
TBF1	FHL1

*S. cerevisiae and A. thaliana interactions determined respectively by database searches of [13] and [14] and represent a range of direct and indirect evidence types, including the presence of binding motifs in regulatory regions and response to TF over-expression. M. musculus interactions determined by evidence gathered in the associated citation

${}^{†}$M. musculus non-core TFs drawn from MA dataset only, while non-core S. cerevisiae and A. thaliana TFs were drawn from the unions of each pair of analyzed datasets