Table 2.
Ventilator settings, physiological data, and blood gas analysis in each section
| During SBT | Noninvasive ventilation | P value* | ||
|---|---|---|---|---|
| Previous method | Novel method | |||
| Ventilation mode | 1.000 | |||
| PSV, n (%) | NA | 50 (83.3) | 51 (85.0) | |
| CPAP, n (%) | NA | 10 (16.7) | 9 (15.0) | |
| FIO2, median (IQR) | 0.3 (0.3–0.4) | 0.3 (0.3–0.4) | 0.3 (0.3–0.4) | 1.000 |
| PEEP, median (IQR), cmH2O | 5 (5–5) | 4 (4–4) | 4 (4–4) | 1.000 |
| PS, median (IQR), cmH2O† | 5 (5–5) | 4 (2–4) | 4 (2–4) | 1.000 |
| Heart rate, mean (SD), bpm | 85.0 (15.5) | 85.0 (14.7) | 85.5 (15.1) | 0.351 |
| Mean blood pressure, mean (SD), mmHg | 81.2 (11.6) | 82.1 (11.6) | 80.5 (11.6) | 0.063 |
| Respiratory Rate, mean (SD), breaths /min | 15.9 (4.9) | 18.2 (5.8) | 19.1 (6.1) | 0.108 |
| Tidal Volume, mean (SD), mL | 528 (157) | 469 (130) | 474 (122) | 0.692 |
| Minute ventilation, mean (SD), L/min | 7.9 (2.3) | 8.1 (3.2) | 8.6 (3.3) | 0.084 |
| RSBI, mean (SD) | 33.6 (16.1) | 43.1 (20.4) | 42.9 (17.0) | 0.939 |
| Total leakage, mean (SD), L/min | NA | 45.1 (11.5) | 36.1 (8.3) | < 0.001 |
| PaO2, median (IQR), mmHg | 87.3 (77.5–100.0) | 86.2 (76.0–100.5) | 89.6 (75.9–97.9) | 0.793 |
| P/F ratio, median (IQR) | 290 (214–364) | 271 (216–335) | 280 (211–342) | 0.601 |
| PaCO2, mean (SD), mmHg | 37.6 (5.7) | 38.2 (5.5) | 38.4 (5.4) | 0.286 |
| PETCO2, mean (SD), mmHg | 35.1 (5.8) | 32.0 (6.3) | 35.7 (5.5) | < 0.001 |
| pH, mean (SD) | 7.43 (0.05) | 7.42 (0.05) | 7.42 (0.05) | 0.610 |
CPAP, continuous positive airway pressure; FIO2, fraction of inspiratory oxygen; NA, not applicable; PaCO2, arterial partial pressure of carbon dioxide; PaO2, arterial partial pressure of oxygen; PEEP, positive end expiratory pressure; PETCO2, end-tidal partial pressure of carbon dioxide; P/F ratio, ratio of arterial oxygen partial pressure to fractional inspired oxygen; PS, pressure support; PSV, pressure support ventilation; RSBI, rapid shallow breathing index; SBT, spontaneous breathing trial
*Compared measurements in patients using the novel method with the previous method
†Among patients who underwent PSV during noninvasive ventilation