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. 2021 Mar 23;118(1):20–36. doi: 10.1093/cvr/cvab115

Figure 3.

Figure 3

Maturation methods and features in engineered cardiac tissue mimics. (Left) Several stimuli and modifications such as controlled electrical pacing, metabolic supplementation, mechanical loading and addition of non-myocytes to tissue engineered constructs have shown to promote (Right) mature cardiac tissue-like features both in morphology and function.