Table 3.
The association between all-cause mortality and NPAR
| NPAR | Non-adjusted | Model I | Model II | |||
|---|---|---|---|---|---|---|
| HR (95% CIs) | p value | HR (95% CIs) | p value | HR (95% CIs) | p value | |
| 30-day all-cause mortality | ||||||
| Tertiles | ||||||
| < 21.58 | 1.0 | 1.0 | 1.0 | |||
| ≥ 21.58, < 26.77 | 1.38 (0.89, 2.13) | 0.1506 | 1.27 (0.82, 1.96) | 0.2917 | 0.99 (0.60, 1.66) | 0.9826 |
| ≥ 26.77 | 2.29 (1.53, 3.43) | < 0.0001 | 2.07 (1.38, 3.12) | 0.0005 | 1.29 (0.77, 2.17) | 0.3262 |
| P for trend | < 0.0001 | 0.0002 | 0.5418 | |||
| Quartiles | ||||||
| < 20.49 | 1.0 | 1.0 | 1.0 | |||
| ≥ 20.49, < 23.94 | 1.55 (0.91, 2.65) | 0.1078 | 1.43 (0.84, 2.45) | 0.1912 | 1.73 (0.91, 3.30) | 0.0956 |
| ≥ 23.94, < 28.33 | 2.07 (1.24, 3.45) | 0.0056 | 1.96 (1.17, 3.28) | 0.0109 | 1.50 (0.80, 2.83) | 0.2101 |
| ≥ 28.33 | 2.87 (1.76, 4.69) | < 0.0001 | 2.54 (1.54, 4.18) | 0.0002 | 2.01 (1.05, 3.87) | 0.0354 |
| P for trend | < 0.0001 | < 0.0001 | 0.2698 | |||
| 90-day all-cause mortality | ||||||
| Tertiles | ||||||
| < 21.58 | 1.0 | 1.0 | 1.0 | |||
| ≥ 21.58, < 26.77 | 1.34 (0.91, 1.98) | 0.1439 | 1.22 (0.82, 1.81) | 0.3200 | 1.06 (0.66, 1.70) | 0.7952 |
| ≥ 26.77 | 2.59 (1.81, 3.68) | < 0.0001 | 2.31 (1.61, 3.31) | < 0.0001 | 1.54 (0.97, 2.46) | 0.0701 |
| P for trend | < 0.0001 | < 0.0001 | 0.0893 | |||
| Quartiles | ||||||
| < 20.49 | 1.0 | 1.0 | 1.0 | |||
| ≥ 20.49, < 23.94 | 1.60 (1.00, 2.58) | 0.0504 | 1.48 (0.92, 2.38) | 0.1077 | 1.86 (1.04, 3.33) | 0.0359 |
| ≥ 23.94, < 28.33 | 1.85 (1.16, 2.94) | 0.0099 | 1.75 (1.09, 2.79) | 0.0195 | 1.41 (0.78, 2.53) | 0.2512 |
| ≥ 28.33 | 3.39 (2.21, 5.20) | < 0.0001 | 2.97 (1.92, 4.58) | < 0.0001 | 2.36 (1.32, 4.23) | 0.0038 |
| P for trend | < 0.0001 | < 0.0001 | 0.0399 | |||
| 180-day all-cause mortality | ||||||
| Tertiles | ||||||
| < 21.58 | 1.0 | 1.0 | 1.0 | |||
| ≥ 21.58, < 26.77 | 1.50 (1.05, 2.15) | 0.0273 | 1.38 (0.96, 1.98) | 0.0821 | 1.36 (0.88, 2.11) | 0.1660 |
| ≥ 26.77 | 2.67 (1.92, 3.73) | < 0.0001 | 2.40 (1.71, 3.36) | < 0.0001 | 1.71 (1.10, 2.66) | 0.0165 |
| P for trend | < 0.0001 | < 0.0001 | 0.0272 | |||
| Quartiles | ||||||
| < 20.49 | 1.0 | 1.0 | 1.0 | |||
| ≥ 20.49, < 23.94 | 1.78 (1.15, 2.76) | 0.0092 | 1.66 (1.07, 2.57) | 0.0236 | 2.18 (1.27, 3.75) | 0.0048 |
| ≥ 23.94, < 28.33 | 1.91 (1.24, 2.95) | 0.0036 | 1.80 (1.17, 2.79) | 0.0080 | 1.66 (0.96, 2.88) | 0.0698 |
| ≥ 28.33 | 3.54 (2.37, 5.29) | < 0.0001 | 3.12 (2.08, 4.68) | < 0.0001 | 2.58 (1.49, 4.47) | 0.0007 |
| P for trend | < 0.0001 | < 0.0001 | 0.0150 | |||
| 365-day all-cause mortality | ||||||
| Tertiles | ||||||
| < 21.58 | 1.0 | 1.0 | 1.0 | |||
| ≥ 21.58, < 26.77 | 1.50 (1.08, 2.10) | 0.0169 | 1.38 (0.99, 1.93) | 0.0610 | 1.40 (0.93, 2.10) | 0.1031 |
| ≥ 26.77 | 2.52 (1.85, 3.45) | < 0.0001 | 2.22 (1.62, 3.04) | < 0.0001 | 1.66 (1.10, 2.51) | 0.0154 |
| P for trend | < 0.0001 | < 0.0001 | 0.0471 | |||
| Quartiles | ||||||
| < 20.49 | 1.0 | 1.0 | 1.0 | |||
| ≥ 20.49, < 23.94 | 1.76 (1.17, 2.65) | 0.0064 | 1.64 (1.09, 2.46) | 0.0182 | 2.20 (1.32, 3.66) | 0.0024 |
| ≥ 23.94, < 28.33 | 1.91 (1.27, 2.86) | 0.0018 | 1.78 (1.18, 2.67) | 0.0056 | 1.80 (1.08, 3.00) | 0.0250 |
| ≥ 28.33 | 3.39 (2.33, 4.95) | < 0.0001 | 2.92 (2.00, 4.28) | < 0.0001 | 2.61 (1.56, 4.37) | 0.0003 |
| P for trend | < 0.0001 | < 0.0001 | 0.0075 | |||
HR: hazard ratio; CI: Confidence interval. Models were derived from Cox proportional hazard regression models
Non-adjusted model adjust for: None
Adjust I model adjust for: age; gender; race
Adjust II model adjust for: Age; gender; race; respiratory rate; MBP; heart rate; ALT; AST; CK-peak; CK-MB-peak; glucose; PT; hemoglobin; RDW; creatinine; potassium; sodium; BUN; WBC; Platelet; CAD; AF; COPD; hypertension; diabetes; prior MI; CHF; CKD; STROKE; SOFA; SAPS II