Table 1.
Overview of cohorts’ characteristics, presented as mean ± (standard deviation)
| AAA | Elderly controls | Young controls | AAA vs elderly controls (p) | Elderly controls vs young controls (p) | |
|---|---|---|---|---|---|
| N | 18 | 22 | 23 | ||
| Age | 70.8 ± (3.4) | 71.4 ± (3.4) | 23.3 ± (3.1) | 0.713 | < 0.001* |
| Height [cm] | 176.6 ± (6.7) | 177.6 ± (6.5) | 182.5 ± (6.6) | 0.783 | 0.011* |
| Weight [kg] | 86.6 ± (10.3) | 81.9 ± (8.7) | 78.3 ± (10.3) | 0.153 | 0.189 |
| BSA [m2] | 2.1 ± (0.1) | 2.0 ± (0.1) | 2.0 ± (0.2) | 0.255 | 0.665 |
| Heart rate [bpm] | 63.2 ± (9.8) | 64.8 ± (12.1) | 62.6 ± (10.0) | 0.627 | 0.473 |
| Stroke volume [ml/min] | 64.4 ± (12.5) | 65.0 ± (17.4) | 79.2 ± (14.5) | 0.903 | 0.005* |
| Systolic blood pressure[mmHg] | 133.4 ± (13.7) | 122.9 ± (14.9) | 110 ± (7.0) | 0.031 | < 0.001* |
| Diastolic blood pressure[mmHg] | 74.3 ± (7.3) | 72.3 ± (7.9) | 58.5 ± (3.8) | 0.44 | < 0.001* |
| Smoking | < 0.001** | < 0.001** | |||
| Current | 2 (11.1%) | 0 (0%) | 0 (0%) | ||
| Quit | 16 (88.2%) | 11 (50%) | 1 (4.3%) | ||
| Never | 0 (0%) | 11 (50%) | 22 (95.6%) | ||
| Diabetes mellitus | 1 | 0.489 | |||
| Yes | 1 (5.5%) | 1 (4.5%) | 0 (0%) | ||
| No | 17 (94.5%) | 21 (95.5%) | 23 (100%) | ||
| Hypertension | 0.125 | < 0.001** | |||
| Yes | 12 (66.6%) | 9 (40.9%) | 0 (0%) | ||
| No | 6 (33.4%) | 13 (59.1%) | 23 (100%) | ||
| Previous cardiac disease | 1 | 0.0491 | |||
| Yes | 4 (22.2%) | 4 (18.2%) | 0 (0%) | ||
| No | 14 (77.8%) | 18 (81.8%) | 23 (100%) | ||
| Previous lung disease | 0.642 | 0.233 | |||
| Yes | 3 (16.6%) | 2 (9.1%) | 0 (0%) | ||
| No | 15 (83.4%) | 20 (90.0%) | 23 (100%) | ||
| Previous cerebrovascular disease | 1 | 0.489 | |||
| Yes | 1 (5.5%) | 1 (4.5%) | 0 (0%) | ||
| No | 17 (94.5%) | 21 (95.5%) | 23 (100%) | ||
| Previous renal disease | 1 | 0.489 | |||
| Yes | 0 (0%) | 1 (4.5%) | 0 (0%) | ||
| No | 18 (100%) | 21 (95.5%) | 23 (100%) | ||
Systolic and diastolic blood pressure reported as average of two measures from carotid ultrasound (PWVcr) performed before CMR examination
AAA abdominal aortic aneurysm, BSA body surface area
*Indicates statistical difference (p < 0.025) with Student t-test; **indicates statistical difference (p < 0.025) with Fisher exact test for categorical data