Table 3.
Results for the whole aorta in the three cohorts
| AAA (N = 18) | Elderly controls (N = 22) | Young controls (N = 23) | AAA vs elderly controls (p) | Elderly controls vs young controls (p) | |
|---|---|---|---|---|---|
| Diameter/BSA [mm m−2] | |||||
| AAo | 17.07 [2.36] | 17.36 ± (1.77) | 13.82 ± (1.29) | 0.9026 | < 0.001* |
| Arch | 16.66 [2.46] | 16.37 ± (1.37) | 13.26 ± (1.03) | 0.4882 | < 0.001* |
| DAo | 15 ± (1.87) | 14.22 ± (1.18) | 10.41 ± (0.92) | 0.1192 | < 0.001* |
| SAA | 13.53 ± (1.32) | 12.12 ± (0.98) | 9.03 ± (0.77) | < 0.001* | < 0.001* |
| IAA | 16.51 ± (2.45) | 9.68 ± (0.98) | 7.64 ± (0.71) | < 0.001* | < 0.001* |
| Peak velocity [m s−1] | |||||
| AAo | 0.46 [0.13] | 0.48 ± (0.11) | 0.8 ± (0.16) | 0.577 | < 0.001* |
| Arch | 0.31 ± ( 0.1) | 0.34 ± (0.08) | 0.61 ± (0.13) | 0.363 | < 0.001* |
| DAo | 0.34 ± (0.11) | 0.41 [0.12] | 0.89 ± (0.12) | 0.005* | < 0.001* |
| SAA | 0.37 [ 0.1] | 0.51 ± (0.09) | 1.06 ± (0.18) | < 0.001* | < 0.001* |
| IAA | 0.18 [0.07] | 0.49 ± (0.12) | 0.65 ± ( 0.1) | < 0.001* | < 0.001* |
| Peak WSS [Pa] | |||||
| AAo | 0.75 ± (0.16) | 0.88 ± (0.21) | 1.63 ± (0.32) | 0.038 | < 0.001* |
| Arch | 0.49 ± (0.12) | 0.55 ± (0.12) | 0.99 ± (0.21) | 0.083 | < 0.001* |
| DAo | 0.59 ± (0.12) | 0.8 [ 0.2] | 1.87 ± (0.24) | < 0.001* | < 0.001* |
| SAA | 0.67 ± (0.14) | 0.99 ± (0.17) | 2.27 ± (0.37) | < 0.001* | < 0.001* |
| IAA | 0.37 ± (0.07) | 1.01 ± (0.24) | 1.43 ± (0.21) | < 0.001* | < 0.001* |
| TAWSS [Pa] | |||||
| AAo | 0.31 ± (0.04) | 0.37 ± (0.06) | 0.44 ± (0.05) | < 0.001* | < 0.001* |
| Arch | 0.2 ± (0.03) | 0.24 ± (0.04) | 0.33 ± (0.04) | 0.003* | < 0.001* |
| DAo | 0.2 ± (0.04) | 0.29 ± (0.05) | 0.54 ± (0.06) | < 0.001* | < 0.001* |
| SAA | 0.22 ± (0.03) | 0.33 ± (0.06) | 0.65 ± (0.09) | < 0.001* | < 0.001* |
| IAA | 0.15 ± (0.02) | 0.31 ± (0.08) | 0.41 ± (0.06) | < 0.001* | < 0.001* |
| OSI [−] | |||||
| AAo | 0.15 ± (0.03) | 0.15 ± (0.02) | 0.09 ± (0.02) | 0.900 | < 0.001* |
| Arch | 0.18 [0.04] | 0.19 ± (0.04) | 0.14 ± (0.05) | 0.775 | < 0.001* |
| DAo | 0.14 ± (0.03) | 0.11 [0.05] | 0.06 ± (0.02) | 0.006* | < 0.001* |
| SAA | 0.09 ± (0.03) | 0.08 ± (0.04) | 0.04 ± (0.02) | 0.392 | < 0.001* |
| IAA | 0.2 ± (0.05) | 0.2 ± (0.08) | 0.24 ± (0.07) | 0.946 | 0.122 |
| RRT [−] | |||||
| AAo | 6.63 ± (1.15) | 5.56 ± (0.92) | 3.07 [0.93] | 0.002* | < 0.001* |
| Arch | 11.79 ± (2.83) | 10.07 ± (2.88) | 5.77 ± (1.81) | 0.065 | < 0.001* |
| DAo | 9.26 ± (1.97) | 5.34 [2.09] | 2.37 ± (0.38) | < 0.001* | < 0.001* |
| SAA | 6.67 ± ( 1.3) | 4.26 [1.86] | 1.85 ± (0.38) | < 0.001* | < 0.001* |
| IAA | 15.44 ± ( 3.4) | 7.84 ± (3.53) | 6.29 ± (2.39) | < 0.001* | 0.091 |
For each segment, maximum diameter normalized by BSA and average values of peak velocity, peak WSS, TAWSS, OSI and RRT computed from 4D flow CMR are reported as mean ± (standard deviation), when the values are not normally distributed, or median [interquartile range] when not
AAo ascending aorta, DAo descending aorta, IAA infrarenal abdominal aorta, SAA suprarenal abdominal aorta
*Indicates p ≤ 0.025