TABLE 4: Distribution of time from triage to clinical outcomes according to study arm.
Arm 1 | Arm 2 | |||||
---|---|---|---|---|---|---|
Time (days) from triage to | MGIT | Xpert | P-value | MGIT | LPA | P-value |
N (IQR) | N (IQR) | N (IQR) | N (IQR) | |||
Sputum collection | 0 (0-0) | 0 (0-0.75) | 0.71 | 0 (0-0) | 0 (0-1.00) | 0.87 |
DST results release | 32.5 (27.2-47.0) | 2.2 (0-2.5) | <0.001 | 34.0 (22-62.0) | 9.0 (7-15.0) | <0.001 |
DST results received by the physician | 55.5 (38.2-103.5) | 7.0 (3-13.3) | <0.001 | 40.2 (27.2-65.7) | 30.0 (9-33.2) | <0.001 |
Changing treatment | 47 (35-87.7) | 30.0 (6.7-42.7) | 0.005 | 69.0 (46-84.0) | 61.0 (34-121.0) | 0.99 |
Treatment that matches with standard reference DST | 40.5 (28.7-76.7) | 15.0 (4.5-38.5) | 0.01 | 54.0 (17-80.5) | 61.4 (19.7-104.7) | 0.78 |
Legend: IQR: interquartile range; DST: drug susceptibility testing; MGIT: BactecTMMGITTM 960 system; Xpert: Xpert® MTB/RIF; LPA: line probe assay.