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. 2022 Mar 18;17(3):e0265476. doi: 10.1371/journal.pone.0265476

Table 4. Clinical outcomes by PVL Case/Control Status.

Characteristic Case N = 51 Control N = 56 P-value 1* P-value 2**
    Sepsis 5 (9.8) 17 (30.4) 16
    Septic Shock 10 (19.6) 11 (19.6)
Previous positive culture (Mean ± SD, Range) 0.3 ± 0.6 (0.0–3.0) 1.5 ± 3.5 (0.0–14.0) 0.02 0.77
Duration of the bacteremia, days (Mean ± SD, Range) 3.4 ± 3.5 (1.0–15.0) 3.0 ± 2.8 (1.0–16.0) 0.57 0.73
Fever (⁰C), T MAX (Mean ± SD, Range) 39.0 ± 0.7 (37.3–41.1) 38.9 ± 0.5 (38.1–40.0) 0.91 0.64
Fever duration, days (Mean ± SD, Range) 4.8 ± 6.5 (0.0–29.0) 2.2 ± 1.9
(1.0–7.0)
0.04 0.03
Length of hospital stay, days (Mean ± SD, Range) 15.4 ± 15.1 (0.0–89.0) 11.4 ± 7.7 (0.0–50.0) 0.74 0.10
Length of ICU stay, days (Mean ± SD, Range) 4.0 ± 5.8 (0.0–21.0) 3.6 ± 5.5
(0.0–22.0)
0.72 0.91
Death Date Known (N, %) 8 (15.7) 10 (17.9) 0.97
Number of positive blood cultures (Mean ± SD, Range) 4.8 ± 4.5 (1.0–20.0) 4.6 ± 3.4
(0.0–18.0)
0.72 0.61
Outcome of Infection (N, %) 0.59
Cured 25 (49.0 33 (58.9)
Expired 11 (21.6) 10 (17.9)
Unknown 15 (29.4) 13 (23.2)

Panton-Valentine Leukocidin.

*P-values in P-value 1 column for categorical variables from chi-squared tests, unless indicated with an asterisk (*) where Fisher’s Exact Test was used; for continuous variables, p-values from Student’s t-test with Satterthwaite adjustment when appropriate.

**P-values in P-value 2 column from Wilcoxon rank-sum tests for non-normal distributions