| Study |
Population |
Intervention (s) |
Comparator |
Outcome |
Results |
| He et al., 2020 N=88 [10] |
ASA I to III Elective unilateral total hip arthroplasty |
Quadratus lumborum block (QLB) with 0.33% Ropivacaine |
QLB with saline |
Primary: pain scores secondary: analgesic consumption side effects 10-meter walking speed at day 6. |
Pain scores were significantly low in the intervention group; reduced analgesic consumption and low incidences of side effects in the intervention group. The 10-Meter walking speed was higher among the intervention group. |
| Kukreja et al., 2019 N=80 [11] |
ASA I to III Unilateral primary total hip arthroplasty |
Spinal Anesthesia with QLB |
Spinal Anesthesia without QLB |
Primary: opioid consumption; secondary: pain scores ambulation distance, patient satisfaction, length of stay |
VAS pain scores were significantly lower in the QLB group at 24 hours. Cumulative Opioid consumption was lower in the QLB group. The Patient Satisfaction score was higher in the QLB group. No difference in pain scores at 12 and 48 hours between the groups. No difference in ambulation distance and duration of hospital stays between two groups |
| Brixel et al., 2021 N=100 [13] |
ASA I to II Elective total hip unilateral arthroplasty |
General Anesthesia plus QLB with Ropivacaine |
General Anesthesia plus QLB with saline |
Primary: Total intravenous Morphine consumption in first 24 hours Secondary: Intraoperative Sufentanil consumption Pain score at extubation and at 2,6,12, and 24 hours. Morphine consumption in the Post Anesthesia Care Unit (PACU) Motor Blockade Time to first standing and ambulation Hospital length of stay Adverse events |
No significant difference in 24-hour morphine consumption between the groups. No statistical difference in all secondary outcomes between the groups. |
| Abduallah et al., 2020 N=60 [12] |
ASA II & III Primary total hip arthroplasty |
Unilateral spinal anesthesia plus real QLB with bupivacaine |
Unilateral spinal anesthesia plus Sham QLB with saline |
Primary: postoperative morphine consumption secondary: Postoperative pain time to the first request of rescue analgesia Patients' satisfaction Postoperative complications |
Significant reduction in postoperative morphine consumption in the intervention group Significant reduction in VAS score in the real QLB group Significant prolongation of the time to the first call for analgesia in the real QLB group No significant differences in the level of patients’ satisfaction and the occurrences of complications between the two groups. |
| Hu et al., 2021, N=80 [14] |
ASA I to III Primary unilateral total hip arthroplasty |
General anesthesia and local infiltration anesthesia with QLB |
General anesthesia and local infiltration anesthesia without QLB |
Primary: Postoperative pain score (VAS) at first six hours after the surgery. Secondary: resting VAS in PACU and at 12, 24,48, and 72 hours after surgery. Intraoperative consumption of opioid postoperative morphine consumption. Frequency of sleep interruption due to pain during the night of the surgery. Time until the "first out of the bed" after surgery quadriceps strength adverse effects |
Lower VAS scores on motion in QLB group 6, 12, and 24 hours after surgery. Lower pain scores at rest in PACU and 2, 6, 12, and 24 hours after surgery in the QLB group. Patients in the QLB group consumed fewer intraoperative opioids and postoperative morphine. Less interruption of sleep in the QLB group. Patients in the QLB group walk out of the bed earlier than the no-QLB group. No significant difference in quadriceps strength and occurrences of adverse effects between the groups. |
