Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 18;8(11):eabi4757. doi: 10.1126/sciadv.abi4757

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY).

This is an open-access article distributed under the terms of the Creative Commons Attribution license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Fig. 3. — (A) Force-directed layout of the REMI-LUAD interactome network. Shape of the nodes represent gene function. Color of the node represents cell type as denoted by the legend. (B) Alluvial plot showing the ratio of paracrine and autocrine signaling interactions occurring between cell types. Thickness of lines represent the number of LR pairs. Full table is available in the Supplementary Materials. (C) Distribution of number of communities with certain cell type compositions. (D) Top 10 most significant enrichments for genes within the tumor-immune-stroma–specific communities and tumor-stroma–specific communities. GeneRatio is the ratio of the number of community-specific genes that overlapped with the gene set to the number of community-specific genes that overlapped with all the gene sets in the collection. Count represents the number of genes.