Table 2.
Outcomes | Anticipated absolute effects* (95% CI) | Relative effect (95% CI) | № of participants (studies) | Certainty of the evidence (GRADE) | |
---|---|---|---|---|---|
Risk with standard care/control | Risk with Remote support | ||||
Stopping exclusive breastfeeding at 4–8 weeks | 458 per 1000 | 394 per 1000 (321–490) | RR 0.86 (0.70–1.07) | 4365 (14 RCTs) | ⊕〇〇〇 VERY LOWa, b, c |
Stopping any breastfeeding at 4–8 weeks | 314 per 1000 | 345 per 1000 (226–468) | RR 1.10 (0.74–1.64) | 3535 (12 RCTs) | ⊕⊕〇〇 LOWb, c |
Stopping exclusive breastfeeding at 3 months | 558 per 1000 | 435 per 1000 (336–474) | RR 0.5 (0.63–0.90) | 2286 (12 RCTs) | ⊕⊕〇〇 LOWb, d |
Stopping any breastfeeding at 3 months | 415 per 1000 | 370 per 1000 (229–434) | RR 0.89 (0.71–1.11) | 1518 (9 RCTs) | ⊕⊕〇〇 LOWb, c |
Stopping exclusive breastfeeding at 6 months | 786 per 1000 | 715 per 1000 (691–746) | RR 0.93 (0.88–0.1.00) | 3488 (11 RCTs) | ⊕⊕〇〇 LOWb, d |
Stopping any breastfeeding at 6 months | 477 per 1000 | 434 per 1000 (387–492) | RR 0.91 (0.81–1.03) | 2275 (7 RCTs) | ⊕⊕〇〇 LOWa, b |
High or unclear risk of bias for incomplete outcomes. Sensitivity analyses restricted to trials of low risk of bias showed a change in significant of findings. Downgraded 1 level.
Substantial unexplained heterogeneity (>60%). Downgraded 1 level.
Wide confidence interval crossing line of no effect (RR < 0.75 or >1.25).
High or unclear risk of bias for allocation concealment. Sensitivity analyses restricted to trials of low risk of bias showed a change in significant of findings. Downgraded 1 level.