Table 1.
Comparison between the different studied subgroups according to the mortality rate, the cyst count/10 HPF and the infectivity rate
| Ia (n = 10) |
Ib (n = 10) |
IIa1 (n = 10) |
IIa2 (n = 10) |
IIa3 (n = 10) |
IIb (n = 10) |
p | ||
|---|---|---|---|---|---|---|---|---|
| Mortality rate | 20.0% | 10.0% | 10.0% | 20.0% | 20.0% | 10.0% | 1.000 | |
| Cyst count/ 10 HPF | ||||||||
| Median (Min – Max) |
10 (8.9–11.8) | 0.9 (0.5–1.4) | 3.1 (2.4–3.8) | 6 (5.2–7.6) | 9.9 (8.8–11) | F = 368.950* | <0.001* | |
| Mean ± SD. | 10.2 ± 0.9 | 0.9 ± 0.3 | 3.1 ± 0.5 | 6.2 ± 0.8 | 9.9 ± 0.7 | |||
| p1 | <0.001* | <0.001* | <0.001* | 0.365 | ||||
| p2 | <0.001* | <0.001* | <0.001* | |||||
| Significance between subgroups | p3 < 0.001*,p4 < 0.001*, p5 < 0.001* | |||||||
| Infectivity rate | 10 (100%) | 10 (100%) | 8 (80%) | 2 (20%) | 10 (100%) | x² = ²3.²57* | MCp<0.001* | |
| FEp1 | – | 0.474 | 0.001* | – | ||||
| FEp2 | – | 0.474 | 0.001* | |||||
| Significance between subgroups | FEp3 = 0.474,FEp4 = 0.001*, p5 = 0.007* | |||||||
χ2: Chi square test MC: Monte Carlo FE: Fisher Exact
F: F for ANOVA test, pairwise comparison between each two subgroups was done using Post Hoc Test (Tukey)
p: p value for comparing between the different studied subgroups
p1: p value for comparing between Ib and IIa1, IIa2, IIa3, IIb
p2: p value for comparing between IIb and IIa1, IIa2, IIa3
p3: p value for comparing between IIa1 and IIa2
p4: p value for comparing between IIa1 and IIa3
p5: p value for comparing between IIa2 and IIa3
*: Statistically significant at p ≤ 0.05
Ia: Healthy control, Ib: Infected control, IIa1: Aluvia-treated (day zero), IIa2: Aluvia-treated (second week), IIa3: Aluvia-treated (eighth week), IIb: Therapeutic control