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. 2022 Mar 16;14(1):2051336. doi: 10.1080/20002297.2022.2051336

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Evaluation of metabolic pathways of HRT samples. Panel a reports on the bar plot representing the EC class abundance based on HRT compartments. The x‐axis represents the different HRT compartments, while the y‐axis indicates the relative abundance of each EC class. The whiskers reported the standard deviation. Panel b shows the bar plot indicating the EC class abundance based on HRT-CSTs. The x‐axis represents the different HRT compartments, while the y‐axis indicates the relative abundance of each EC class. The whiskers report the standard deviation. Panel c reports the multivariate analysis calculated on the two enzyme classes EC 1.7.1.4 and EC 1.1.1.28 through MaAslin2 software and represented with bar plot. The MaAsLin2 model are fitted with the enzyme classes, as well as HRT-CSTs, sampling methods as well as bioproject, and geographical origin.