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. 2022 Mar 11;2022:1384609. doi: 10.1155/2022/1384609

Table 4.

Expression of biomarkers of cognitive function in the two groups.

Treatments N NSE S100β Aβ
Before surgery 10 days after surgery Before surgery 10 days after surgery Before surgery 10 days after surgery
Ultrasound-guided combined lumbar plexus-sciatic nerve block 58 8.78 ± 1.55 10.23 ± 0.26a∗ 237.24 ± 33.31 267.37 ± 41.28a∗ 259.15 ± 30.50 286.81 ± 21.75a∗
Combined spinal-epidural anesthesia 62 9.09 ± 1.93 10.60 ± 0.22a 242.63 ± 26.83 283.93 ± 26.05a 256.27 ± 30.25 298.28 ± 37.60a
T 0.966 8.434 0.979 2.646 0.519 2.027
P 0.336 <0.0001 0.330 0.009 0.605 0.045

indicates P < 0.05 compared with combined spinal-epidural anesthesia; a indicates P < 0.05 compared with that before surgery.