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. 2022 Mar 11;2022:1384609. doi: 10.1155/2022/1384609

Table 5.

Proinflammatory cytokine levels in the two groups.

Treatments N IL-6 TNF-α IL-1β Hs-CRP
Before surgery 10 days after surgery Before surgery 10 days after surgery Before surgery 10 days after surgery Before surgery 10 days after surgery
Ultrasound-guided combined lumbar plexus-sciatic nerve block 58 52.11 ± 12.01 102.30 ± 36.98a∗ 48.35 ± 13.47 80.88 ± 22.78a∗ 35.72 ± 3.82 45.54 ± 5.68a∗ 18.42 ± 0.19 23.93 ± 2.60a∗

Combined spinal-epidural anesthesia 62 53.86 ± 11.85 124.53 ± 41.31a 44.17 ± 11.11 101.56 ± 27.04a 35.66 ± 4.83 50.90 ± 5.59a 18.5 ± 0.29 28.02 ± 2.17a

T 0.803 3.098 1.859 4.515 0.075 5.208 1.774 9.378

P 0.4235 0.0024 0.0655 <0.0001 0.940 <0.0001 0.079 <0.0001

indicates P < 0.05 compared with combined spinal-epidural anesthesia; aindicates P < 0.05 compared with that before surgery.