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. 2022 Mar 11;2022:4978556. doi: 10.1155/2022/4978556

Figure 2.

Figure 2

THC reduces the production of IL-6, TNF-α, MIP-2, IP-10, and nitrite in P. a. LPS–stimulated BV2 microglial cells. BV2 microglial cells were untreated (the mock group) or pretreated with THC (10, 20, or 40 μM) for 1.5 h before being stimulated by P. a. LPS (0.1 μg/ml) for 24 h. The production of (a) IL-6, (b) TNF-α, (c) MIP-2, (d) IP-10, and (e) nitrite was detected using ELISA. The experimental quantitative data are presented in terms of the mean ± SD (n = 3). The mock group was considered as a control group. Bars with the same letter represent no significant difference between the groups. Bars with different letters indicate a statistically significant (p < 0.05) difference between the groups.