Table 4.

Metabolic pathways associated with potential biomarkers in serum.

Metabolic pathway	Total	Expected	Hits	Raw p	Holm adjust	FDR	Impact
Sphingolipid metabolism	21	0.18	3	0.00056	0.04726	0.0269	0.158
Linoleic acid metabolism	5	0.04	2	0.00064	0.05317	0.0269	1.0
Glycerophospholipid metabolism	36	0.30	3	0.00281	0.23015	0.0786	0.216
Fatty acid biosynthesis	47	0.39	3	0.00604	0.48925	0.1268	0.015
Biosynthesis of unsaturated fatty acids	36	0.30	2	0.03484	1.0	0.4878	0.0
Arachidonic acid metabolism	36	0.30	2	0.03484	1.0	0.4878	0.020
Alpha-linolenic acid metabolism	13	0.11	1	0.10409	1.0	1.0	0.0
Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	14	0.12	1	0.11167	1.0	1.0	0.004
Glutathione metabolism	28	0.23	1	0.21173	1.0	1.0	0.027
Fatty acid elongation	39	0.33	1	0.28293	1.0	1.0	0.0
Fatty acid degradation	39	0.33	1	0.28293	1.0	1.0	0.0