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CF-1, CD-1, and CFW mouse strain survival assessed for 10 days in the peritonitis model with a single local intraperitoneal injection of 10 mg of IgG or placebo treatment (5% dextrose) against a lethal dose of 107 CFU of P. aeruginosa IFO-3455 injected intraperitoneally (n = 10 to 35 animals/group). IgG treatment resulted in significantly increasing survival compared to placebo (5% dextrose) treatment in all three mouse strains (ANOVA with Tukey’s test; P < 0.001).
