FIG. 5.
ELISA detection of human IgG levels in murine serum (⧫) and peritoneal lavage fluid (▵) after bacterial challenge following intraperitoneal injection of IgG and intraperitoneal lethal injections of P. aeruginosa IFO-3455 (107 CFU, n = 3 or 4 animals per time point in each group) for 7 days. Human IgG is detectable rapidly in mouse serum after intraperitoneal administration and remains detectable by ELISA methods in both serum and mouse peritoneal lavage fluid for up to 7 days. (Inset) Human IgG levels in mouse serum and peritoneal lavage fluid in the first 12 h postadministration.