FIGURE 4.

QUIQI increases the sensitivity of MRI data analysis. The effect of QUIQI on the analysis of brain‐related differences was assessed using statistical F tests of the dependence of the MRI data with age (a). Compared with OLS analyses, QUIQI leads to region‐specific decreases or increases in F‐scores due to the restored noise homoscedasticity (b). Exclusion of the 30% most degraded images was required to restore noise homoscedasticity in OLS analyses. WLS analyses yield higher age‐sensitivity over the whole brain (c)