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. 2022 Feb 4;41(12):1718–1726. doi: 10.1038/s41388-021-02100-0

Fig. 5. Mice deficient in Fdxr, Trp53, or both are prone to lipid accumulation in the blood.

Fig. 5

A The levels of ABCA1, SREBP1/2, MVD, MVK, and actin were measured in WT, Fdxr+/−, Trp53+/−, and Fdxr+/−;Trp53+/− mouse liver tissues. B–E The levels of blood cholesterol (B), triglycerides (C), LDL (D), and HDL (E) in 43-week-old WT, Fdxr+/−, Trp53+/−, and Fdxr+/−;Trp53+/− mice (n = 5). Values are mean ± SEM and analyzed by 2-tailed t-test.