FIGURE 2.

Temporal properties analysis in two discrete functional connectivity states of the hippocampal network. (a) State I is characterized by anterior hippocampal network dominated pattern, which represents positive coupling within/between modules of the medial temporal lobe (MTL) and anterior extra‐MTL. (b) State II is characterized by posterior hippocampal network dominated pattern, which represents positive coupling within posterior extra‐MTL module, as well as positive correlation between posterior extra‐MTL module and each other modules. The percentage of fractional windows (c), mean dwell time (d), and number of transitions (e) in each state is displayed for the healthy controls (HC), temporal lobe epilepsy with memory intact (TLE‐MI) patients, and TLE with memory deficit (TLE‐MD) patients. All of the significance levels were set to p < .05 with multiple comparisons correction. *p < .05, **p < .01, ***p < .001; error bars represent SDs. AMYG, amygdala; ANG, angular gyrus; FUS, anterior fusiform gyrus; ITC, anterior inferior temporal cortex; OFC, lateral orbitofrontal cortex; PCC, posterior cingulate cortex; PHC, parahippocampal cortex; PRC, perirhinal cortex; PREC, precuneus; RSC, retrosplenial cortex