Fig. 1. Phenotypic and genetic correlations between the wellbeing index score, its subcomponents and negative mental health indicators in UK Biobank.

All correlations reported here are statistically significant after Bonferroni correction for multiple testing, although many have low (r = 0.3–0.5) to moderate (r = 0.5–0.7) effect size. Manhattan plots for each GWAS are provided in Figure S6.