Table 1.
Robustness of the analysis methods.
| Dwell-time analysis | Visitation analysis | Average-rate analysis | ||||
|---|---|---|---|---|---|---|
| Recommended conditions for distingushing | ||||||
| The mechanism | Single steps | The mechanism | Single steps | The mechanism | Single steps | |
| SNR | > 1 | > 1 | > 0.1 | > 1 | > 0.1 | > 0.1 |
| Sampling rate | > 10×a | > 20× | > 1× | > 2× | > 1× | > 5× |
| LE (stochastic) | > 0.7 | > 1 | < 1 | 1 | > 0.3 | > 0.7 (1b) |
| LE (specific) | > 0.3 | 1 | > 0.3 | 1 | > 0.3 | 1 |
| Photobleaching | < 3%a | < 0.1% | 3% | < 2% | < 3% | < 2% |
aCompared to the fastest rate.
b1 % to obtain the correct conversion site.