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Generation and features of the PT-MBD2-KO mouse model
(A) Breeding procedure for the creation of PT-MBD2-KO mice. (B) PCR-based genotyping of wild-type and floxed alleles of MBD2 and PEPCK-Cre allele. (C) Representative immunoblots for the expression of MBD2 and GAPDH. (D) Densitometry analysis of proteins signals, and normalized to internal control of GAPDH. Data are expressed as means ± SD (n = 6). #p < 0.05 versus sham group. ∗p < 0.05 versus PT-MBD2-WT with UUO group.
