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View full-text article in PMC

. 2022 Mar 1;25(4):103994. doi: 10.1016/j.isci.2022.103994

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© 2022 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Relationship between material/substrate type and Candida biofilm development

Representative microscopy of acrylic (Poly(methyl methacrylate) - PMMA) and titanium surface topography evaluated by white light 3D profilometry (left side)

Scanning electron microscopy (SEM) images (right side) at 1.5 h (adhesion) and 48 h (maturation) of C. albicans biofilm formed on PMMA (top) and titanium (bottom). White arrows indicate the presence of hyphae, which were prevalent in both materials at 48 h. Overall, the similar surface roughness of both materials and the presence of environment fluids (saliva and blood plasma) culminated in no difference for Candida adhesion and growth for the two tested substrates. Reprinted (adapted) from ref (Cavalcanti et al., 2016a; 2016b); Copyright (2016), with permission from Elsevier (License number: 5117881126618).