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Comparison of IC50 and Ki values of β-lactamase inhibitors for FAR-1 and TEM-1 β-lactamases
| β-Lactamase | Clavulanic acid
|
Sulbactam
|
Tazobactam
|
|||
|---|---|---|---|---|---|---|
| IC50 (μM) | Ki (μM) | IC50 (μM) | Ki (μM) | IC50 (μM) | Ki (μM) | |
| FAR-1 | 0.3 | 1.3 | 600 | 180 | 20 | 4.3 |
| TEM-1 | 0.08 | 0.1 | 6.1 | 0.9 | 0.1 | 0.01 |
