. 2022 Feb 15;298(4):101732. doi: 10.1016/j.jbc.2022.101732

Table 3.

Comparison of glycosphingolipids in normal human stomach and human gastric adenocarcinoma

Trivial name	Glycosphingolipid structure	Normal stomach^a	Gastric cancer	BabA binding^b
Globotetra	GalNAcβ3Galα4Galβ4Glcβ1Cer	+	+
Lactotetra	Galβ3GlcNAcβ3Galβ4Glcβ1Cer^c	+	+
Neolactotetra	Galβ4GlcNAcβ3Galβ4Glcβ1Cer^c	+	+
x₂ penta	GalNAcβ3Galβ4GlcNAcβ3Galβ4Glcβ1Cer^c	+	+
H type 1 penta	Fucα2Galβ3GlcNAcβ3Galβ4Glcβ1Cer^c	+	+	+
H type 2 penta	Fucα2Galβ4GlcNAcβ3Galβ4Glcβ1Cer	+	+
Le^a penta	Galβ3(Fucα4)GlcNAcβ3Galβ4Glcβ1Cer	+	−
Le^x penta	Galβ4(Fucα3)GlcNAcβ3Galβ4Glcβ1Cer	+	+
P1 penta	Galα4Galβ4GlcNAcβ3Galβ4Glcβ1Cer^d	−	+
Neolactohexa	Galβ4GlcNAcβ3Galβ4GlcNAcβ3Galβ4Glcβ1Cer^c	+	+
Le^b hexa	Fucα2Galβ3(Fucα4)GlcNAcβ3Galβ4Glcβ1Cer^c	+	−	+
Le^y hexa	Fucα2Galβ4(Fucα3)GlcNAcβ3Galβ4Glcβ1Cer	+	+
A type 2 hexa	GalNAcα3(Fucα2)Galβ4GlcNAcβ3Galβ4Glcβ1Cer	+	+
H type 2 hepta	Fucα2Galβ4GlcNAcβ3Galβ4GlcNAcβ3Galβ4Glcβ1Cer	+	−
A type 1 hepta	GalNAcα3(Fucα2)Galβ3(Fucα4)GlcNAcβ3Galβ4Glcβ1Cer^c	+	−	+
A type 2 hepta	GalNAcα3(Fucα2)Galβ4(Fucα3)GlcNAcβ3Galβ4Glcβ1Cer	+	−
A type 2 octa	GalNAcα3(Fucα2)Galβ4GlcNAcβ3Galβ4GlcNAcβ3Galβ4Glcβ1Cer	+	−
P1 hepta	Galα4Galβ4GlcNAcββ3Galβ4GlcNAcβ3Galβ4Glcβ1Cer^d	−	+
P1 deca	Galα4Galβ4GlcNAcβ3(Gala4Galβ4GlcNAcβ6)Galβ4GlcNAcβ3Galβ4Glcβ1Cer^d	−	+

Data from the blood group A(Rh+)P human stomach reported in Ref. (14).

Compounds recognized by H. pylori BabA adhesin.

The compounds have been characterized as H. pylori binding in prevoius studies (reviewed in Ref. ((3).

Marks the compounds present in the human gastric adenocarcinoma only.