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. 2022 Mar 18;23:110. doi: 10.1186/s12882-022-02731-9

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Comparison of Cystatin C levels based on the KDIGO AKI definition. A Box and whisker plots showing the median (interquartile range) and range of serum Cystatin C with the individual data points overlaid. Differences between groups were compared using Wilcoxon rank-sum test with the p values presented on the graphs. B Receiver operating characteristic (ROC) curve to measure the association between the biomarker level and AKI status. Serum Cystatin C had a higher area under the receiver operating characteristic (ROC) curve (AUROC) using sKDIGO compared to KDIGO