Table 1.
Demographic and clinical characteristics of the whole sample and ATN groups
| Whole sample | ATN groups | |||
|---|---|---|---|---|
| Normal | AD | SNAP | ||
| N | 94 | 24 | 15 | 43 |
| Sex n (%) men | 37 (39.36) | 11 (45.80) | 5 (33.30) | 18 (41.90) |
| Age in years (mean/SD) | 60.74 (3.42) | 59.83 (2.55) | 59.83 (2.55) | 60.30 (4.17) |
| Schooling years (mean/SD) | 12.05 (5.08) | 12.42 (5.49) | 12.42 (5.49) | 11.86 (4.39) |
| MMSE (mean/SD) | 28.00 (1.50) | 28.13 (1.57) | 27.80 (1.61) | 28.00 (1.50) |
| MCI type n (%) aMCI | 46 (48.94) | 7 (29.16) | 9 (60.00) | 21 (48.84) |
ATN groups: (1) Normal: normal AD biomarkers (A-T-N-); (2) AD: Alzheimer’s disease continuum (including A+T-N-, A+T+N-, A+T+N+, and A+T-N+); and (3) SNAP: non-AD pathologic changes (including A-T+N-, A-T-N+, and A-T+N+), where A refers to aggregated Aβ, T to aggregated tau, and N to MRI neurodegeneration or neuronal injury
MMSE Mini-Mental State Examination, SD Standard deviation, MCI Mild cognitive impairment, aMCI Amnestic mild cognitive impairment