Table 4. ROC curve analysis of pre-hemadsorption laboratory parameters in predicting the mortality among the patients.

ROC: receiver operating characteristic; HAD: hemadsorption; PPV: positive predictive value; NPV: negative predictive value; IL: interleukin; APACHE: Acute Physiology and Chronic Health Evaluation; PMR: predicted mortality rate of the study population calculated based on APACHE score

Pre-HAD parameters	Cut-off	Sensitivity (95% CI)	Specificity (95% CI)	PPV (95% CI)	NPV (95% CI)	AUC (95% CI)	P-value
IL-10	≤125.3	73.08 (52.2–88.4)	83.33 (35.9–99.6)	95 (75.8–99.1)	41.7 (25.7–59.7)	0.75 (0.566–0.885)	0.0406
APACHE score	>30	73.08 (52.2–88.4)	100 (54.1–100.0)	0	46.2 (31.3–61.8)	0.907 (0.751–0.981)	<0.0001
PMR	>70.33	69.23 (48.2–85.7)	100 (54.1–100.0)	0	42.9 (29.6–57.2)	0.907 (0.751–0.981)	<0.0001