Table 2.
Multivariable competing risk models for waitlist mortality
| Univariable Analyses | Race + Deprivation | Race + Deprivation + Insurance | Race + Deprivation + Initial Lab MELD/PELD + Insurance | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
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| Variable | SHR | 95% CI | P Value | SHR | 95% CI | P Value | SHR | 95% CI | P Value | SHR | 95% CI | P Value |
| Race/ethnicity | ||||||||||||
| Non-Hispanic White | REF | REF | REF | REF | ||||||||
| Black | 1.44 | 1.18, 1.75 | <0.001 | 1.39 | 1.13, 1.71 | <0.01 | 1.28 | 1.04, 1.58 | 0.02 | 1.12 | 0.91, 1.39 | 0.29 |
| Hispanic | 1.48 | 1.25, 1.76 | <0.001 | 1.43 | 1.19, 1.72 | <0.001 | 1.30 | 1.08, 1.57 | 0.01 | 1.21 | 1.00, 1.47 | 0.05 |
| Other | 1.46 | 1.14, 1.88 | <0.01 | 1.46 | 1.14, 1.87 | <0.01 | 1.42 | 1.11, 1.82 | 0.01 | 1.31 | 1.02, 1.69 | 0.04 |
| Neighborhood deprivation | 1.09 | 1.02, 1.16 | 0.01 | 1.03 | 0.97, 1.11 | 0.31 | 0.99 | 0.92, 1.06 | 0.74 | 0.98 | 0.91, 1.05 | 0.52 |
| Insurance | ||||||||||||
| Private | REF | REF | REF | |||||||||
| Public | 1.58 | 1.36, 1.84 | <0.001 | 1.48 | 1.25, 1.76 | <0.001 | 1.55 | 1.30, 1.84 | <0.001 | |||
| Other | 1.52 | 0.96, 2.41 | 0.08 | 1.51 | 0.95, 2.40 | 0.08 | 1.65 | 1.03, 2.64 | 0.04 | |||
| Initial lab MELD/PELD | 1.05 | 1.04, 1.05 | <0.001 | 1.05 | 1.04, 1.05 | <0.001 | ||||||
Abbreviations: MELD, Model for End-stage Liver Disease; PELD, Pediatric End-stage Liver Disease; REF: Reference category; SHR: subhazard ratio
To better understand the effect of race/ethnicity on waitlist mortality, we used a hypothesized causal model (Figure 1) to select the set of covariates for the models. In these models, we included neighborhood deprivation, insurance status, and initial PELD/MELD (as a surrogate for disease severity at the time of listing).