Fig. 5.

Scatter plots of the relationship between POD and BEPOD at different exposure time points from 3 h to 13 weeks. The red line represents x = y, and the blue lines represent 10-fold difference between the BMD values. (a)-(g) are the scatterplots of BEPOD and POD at 3-hour, 6-hour, 9-hour, 24-hour, 4-day, 8-day, and-15 day respectively. (h) is the scatterplot of BEPOD and POD at the same exposure time points. The blue dots are data from (Thomas et al. 2013b) that the BEPOD and apical POD are both at 5 day, 2 weeks, 4 weeks and 13 weeks. The orange dots are data from Open TG-Gates (Igarashi et al. 2015) that the BEPOD and apical POD are both at 29 day. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)