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Clinical efficacy of IL-12 and IL-23 blockade (ustekinumab). Patient before starting therapy (a, b), after 8 weeks from the introduction of the IL-12/IL-23 blocker (c, d), and after 16 weeks after the introduction of the IL-12/IL-23 blocker (e, f). Pictures presented are part of the private collection of Vesna M. Milicic and Ana B. Ravic Nikolic.
