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. Author manuscript; available in PMC: 2023 Apr 1.
Published in final edited form as: J Hepatol. 2021 Dec 23;76(4):921–933. doi: 10.1016/j.jhep.2021.12.014

Figure 1:

Figure 1:

Cholangiocyte- selective knockout of p300 attenuates DR and biliary fibrosis. (A) Immunohistochemistry for CK19; (B) Immunoblotting for EpCAM; (C) Immunohistochemistry for SOX9; (D) Masson’s Trichrome staining; (E) Hydroxyproline assays; (F) Picro-Sirius red staining; and (G) Serum ALP in p300fl/fl and Krt19Cre/p300fl/fl animals with sham or BDL surgery. (n=5- 7 animals/group). Graph bars represent SEM. (A-D),(F-G) Mann-Whitney test *p<0.05,**p<0.01;(E) one-way ANOVA with Bonferroni comparison *p<0.05,****p<0.001.