Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jan 13;24(3):247–260. doi: 10.1007/s11886-022-01641-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 1 — Overview of cardiac functions and pathophysiological pathways in cardiotoxicity for which emerging PET tracers are proposed to have diagnostic or prognostic function. Leading examples of tracers for each of pathway are discussed in the following sections and their molecular or biochemical targets are indicated in the panels. Abbreviations: CXCR4 = C-X-C chemokine receptor type 4; TSPO = 18-kDa translocator protein; mPTP = mitochondrial permeability transition pore; ROS = reactive oxygen species; LAT = L-amino acid transporter; NET = norepinephrine transporter; β-AR = β-adrenergic receptor; FAP = fibroblast activation protein; GLUT = glucose transporter; HK = hexokinase; MCT = monocarboxylate transporter; LDH = lactate dehydrogenase; FA = fatty acid; FATP = fatty acid transport protein; FACS = fatty acid-CoA synthetase; CPT = carnitine palmitoyltransferase; CT = carnitine acyltransferase; TCA = tricarboxylic acid; AcAc = acetoacetate; β-HB = β-hydroxybutyrate