Table 1.
Characteristics of subjects and of nociceptive reflex.
| n = 21 | |
|---|---|
| Age, years | 28 (IQR 25–35) |
| Female sex, n (%) | 11 (52%) |
| Anticonception | |
| Estrogen progestin pill | 5 (24%) |
| Estrogen progestin vaginal ring | 1 (5%) |
| Progestin implanon | 1 (5%) |
| Copper contraceptive coil | 1 (5%) |
| Menopause | 3 (14%) |
| Body mass index (kg/m2) | 23.9 ± 2.1 |
| Heart rate per minute | 68 ± 11 |
| Systolic blood pressure, mmHg | 120 ± 14 |
| Morphine aerosol, n (%) | 9 (43%) |
| Fentanyl aerosol, n (%) | 3 (14%) |
| Intravenous morphine, n (%) | 9 (43%) |
| Baseline cortisol (nmol/L) | 458 ± 267 |
| Baseline copeptin (pmol/L) | 5.1 ± 2.7 |
| Stimulation time of LS, min | 19 (IQR 12.5–25.5) |
| Intensity of stimulation during LS, mA | 22 ± 11 |
| VAS at end of LS | 47 ± 6 |
| Stimulation time of OS, minutes | 2 (IQR 0.75–5.0) |
| Intensity of stimulation during OS, mA | 25 ± 12 |
| VAS at O + 7 | 52 ± 1.7 |
n = 21 includes only subjects who completed all test sessions and had a complete data set available.
Normally distributed data is shown as mean ± SD, otherwise as median (IQR).
LS learning session, OS opioid session, VAS visual analog pain scale rating from 0 to 100, 0 meaning no pain and 100 the worst imaginable pain.