Table 2.
The association between diabetes status and microvascular/macrovascular complications and neuropsychological outcomes stratified by age.
| Model Outcome | Covariate | Ages 0-20 OR (95% CI) | Ages 20-40 OR (95% CI) | Ages 40-60 OR (95% CI) | Ages 60 + OR (95% CI) |
|---|---|---|---|---|---|
| Mental Health Disorder | Type 1 Diabetes (reference: no diabetes) | 1.14 (1.10, 1.17) a | 1.04 (1.03, 1.06) a | 0.98 (0.97, 0.99) a | 0.94 (0.93, 0.95) a |
| Type 2 Diabetes (reference: no diabetes) | 1.31 (1.28, 1.35) a | 1.24 (1.22, 1.26) a | 1.11 (1.10, 1.12) a | 1.01 (1.01, 1.02) a | |
| Microvascular/Macrovascular complications (reference: none) | 1.37 (1.28, 1.46) | 1.31 (1.28, 1.34) | 1.43 (1.41, 1.44) | 1.61 (1.60, 1.63) | |
| Cognitive Disorder | Type 1 Diabetes (reference: no diabetes) | N/A | N/A | 0.89 (0.85, 0.94) | 0.87 (0.85, 0.88) |
| Type 2 Diabetes (reference: no diabetes) | N/A | N/A | 0.96 (0.93, 0.99) | 0.89 (0.88, 0.90) | |
| Microvascular/Macrovascular complications (reference: none) | N/A | N/A | 2.45 (2.36, 2.54) | 2.16 (2.13, 2.19) | |
| Chronic Pain | Type 1 Diabetes (reference: no diabetes) | 1.06 (1.03, 1.09) a | 1.02 (1.01, 1.04) a | 0.94 (0.93, 0.95) a | 0.92 (0.91, 0.93) a |
| Type 2 Diabetes (reference: no diabetes) | 1.44 (1.41, 1.48) a | 1.34 (1.33, 1.36) a | 1.12 (1.11, 1.13) a | 1.05 (1.04, 1.05) a | |
| Microvascular/Macrovascular complications (reference: none) | 1.46 (1.37, 1.55) | 1.35 (1.32, 1.38) | 1.51 (1.50, 1.53) | 1.77 (1.75, 1.78) | |
| Addiction | Type 1 Diabetes (reference: no diabetes) | 1.03 (0.97, 1.09) | 1.08 (1.06, 1.11) a | 0.83 (0.82, 0.84) a | 0.83 (0.81, 0.84) a |
| Type 2 Diabetes (reference: no diabetes) | 1.15 (1.09, 1.21) | 1.24 (1.22, 1.27) a | 0.99 (0.98, 1.00) a | 0.94 (0.93, 0.95) a | |
| Microvascular/Macrovascular complications (reference: none) | 1.51 (1.36, 1.68) | 1.33 (1.29, 1.37) | 1.58 (1.56, 1.60) | 1.58 (1.56, 1.60) | |
| Sleep Disorder | Type 1 Diabetes (reference: no diabetes) | 0.97 (0.91, 1.04) a | 0.92 (0.90, 0.95) a | 0.93 (0.92, 0.94) a | 0.98 (0.97, 1.00) a |
| Type 2 Diabetes (reference: no diabetes) | 1.54 (1.46, 1.63) a | 1.39 (1.36, 1.42) a | 1.25 (1.24, 1.26) a | 1.14 (1.12, 1.15) a | |
| Microvascular/Macrovascular complications (reference: none) | 1.54 (1.38, 1.72) | 1.41 (1.36, 1.46) | 1.49 (1.48, 1.50) | 1.52 (1.50, 1.53) |
OR, Odds ratio; CI, confidence interval; N/A, Not Applicable.
Bold represents a statistically significant (P-Value<0.05) difference in odds between individuals with type 1 diabetes and without diabetes, between individuals with type 2 diabetes and without diabetes, and between individuals with and without microvascular/macrovascular complications based on Wald Tests.
a
Represents a statistically significant (P-Value<0.05) difference in odds between individuals with type 1 diabetes and individuals with type 2 diabetes based on Wald Tests.