Table 5.

Univariable and multivariable analyses of CSS in Luminal BC with HER2-negativity.

Characteristics	n	Univariate analysisHR (95% CI)	p-Value	Multivariate analysisHR (95% CI)	p-Value
Age (years)			0.068
<50	346	1
≥50	362	1.765 (0.958-3.249)
BMI			0.674
<24	446	1
≥24	262	1.137 (0.626-2.064)
Menopausal status			0.2
Pre-	362	1
Post-	327	1.477 (0.813-2.682)
Tumor size			0.008		0.774
<2cm	449	1		1
≥2cm	259	2.222 (1.234-4.001)		1.185 (0.372-3.773)
Lymph node metastasis			<0.001		0.846
Negative	607	1		1
Positive	101	4.620 (2.557-8.349)		1.142 (0.301-4.337)
TNM grade
I	422	1		1
II	224	1.297 (0.602-2.794)	0.507	1.136 (0.280-4.604)	0.858
III	62	8.634 (4.401-16.938)	<0.001	5.401 (0.864-33.769)	0.071
Histology type
Infiltrating ductal carcinoma	635	1
Infiltrating lobular carcinoma	15	0	0.965
Others	57	1.101 (0.394-3.072)	0.855
Luminal subtype			0.032		0.002
Luminal A	316	1		1
Luminal B	392	2.026 (1.063-3.859)		2.912 (1.464-5.794)
Operation type
Modified radical mastectomy	375	1		1
Breast-conserving surgery	249	0.358 (0.157-0.818)	0.015	0.596 (0.239-1.484)	0.266
Mammectomy	72	0.354 (0.084-1.482)	0.155	0.577 (0.126-2.628)	0.477
Others	12	10.833 (4.734-24.79)	<0.001	2.964 (1.055-8.331)	0.039
Chemotherapy
Neoadjuvant chemotherapy	66	1		1
Adjuvant chemotherapy	362	0.229 (0.108-0.484)	<0.001	0.727 (0.286-1.847)	0.503
No chemotherapy	280	0.318 (0.152-0.665)	0.002	1.902 (0.592-6.114)	0.280
Radiotherapy			0.829
No	310	1
Yes	398	1.067 (0.591-1.928)
NLR			<0.001		<0.001
<2.2	423	1		1
≥2.2	285	4.252 (2.196-8.233)		3.999 (2.002-7.987)
CAR			<0.001		<0.001
<0.07	610	1		1
≥0.07	98	8.066 (4.489-14.493)		6.563 (3.558-12.106)

All of our variables with p-values less than 0.05 are in bold