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. 2022 Mar 3;14:821235. doi: 10.3389/fnagi.2022.821235

TABLE 1.

General characteristics of the participants.

Characteristics Total participants
COVID-19 patients
COVID-19 (n, %) Control (n, %) P-value Severe morbidity (n, %) Mild morbidity (n, %) P-value
Total number 8,070 (100.0) 32,280 (100.0) 569 (100.0) 7,501 (100.0)
Age (years) 1.000 <0.001*
0–9 81 (1.0) 324 (1.0) 6 (1.1) 75 (1.0)
10–19 276 (3.4) 1,104 (3.4) 6 (1.1) 270 (3.6)
20–29 2,057 (25.5) 8,228 (25.5) 31 (5.5) 2,026 (27.0)
30–39 832 (10.3) 3,328 (10.3) 25 (4.4) 807 (10.8)
40–49 1,036 (12.8) 4,144 (12.8) 30 (5.3) 1,006 (13.4)
50–59 1,567 (19.4) 6,268 (19.4) 71 (12.5) 1,496 (19.9)
60–69 1,199 (14.9) 4,796 (14.9) 116 (20.4) 1,083 (14.4)
70–79 617 (7.7) 2,468 (7.7) 118 (20.7) 499 (6.7)
80+ 405 (5.0) 1,620 (5.0) 166 (29.2) 239 (3.2)
Sex 1.000 <0.001*
Men 3,236 (40.1) 12,944 (40.1) 306 (53.8) 2,930 (39.1)
Women 4,834 (59.9) 19,336 (59.9) 263 (46.2) 4,571 (60.9)
Income 1.000 <0.001*
1 (low) 3,105 (38.5) 12,420 (38.5) 196 (34.5) 2,909 (38.8)
2 2,347 (29.1) 9,388 (29.1) 161 (28.3) 2,186 (29.1)
3 (high) 2,618 (32.4) 10,472 (32.4) 212 (37.3) 2,406 (32.1)
CCI score <0.001* <0.001*
0 6,725 (83.3) 29,637 (91.8) 333 (58.5) 6,392 (85.2)
1 869 (10.8) 1,514 (4.7) 110 (19.3) 759 (10.1)
≥2 476 (5.9) 1,129 (3.5) 126 (22.1) 350 (4.7)
Hypertension 1,657 (20.5) 6,535 (20.2) 0.331 275 (48.3) 1,382 (18.4) <0.001*
Diabetes 969 (12.0) 3,406 (10.6) <0.001* 186 (32.7) 783 (10.4) <0.001*
Alzheimer’s disease 309 (3.8) 647 (2.0) <0.001* 117 (20.6) 192 (2.6) <0.001*
Parkinson’s disease 52 (0.6) 109 (0.3) <0.001* 275 (48.3) 1,382 (18.4) <0.001*

CCI, Charlson comorbidity index; COVID-19, Coronavirus Disease 2019.

*Chi-squared or Fisher’s exact test. Significance at p < 0.05.

CCI score was assessed excluding dementia and diabetes.