TABLE 3.

Crude and adjusted odds ratios of Alzheimer’s disease and Parkinson’s disease for morbidity in COVID-19 participants.

Characteristics	Severe participants (exposure/total, %)	Mild participants (exposure/total, %)	Odds ratios (95% confidence interval) for morbidity
			Crude	P-value	Model 1†	P-value	Model 2‡	P-value
Alzheimer’s disease
AD	117/569 (20.6%)	192/7,501 (2.6%)	9.85 (7.68–12.64)	<0.001*	2.49 (1.87–3.32)	<0.001*	2.21 (1.64–2.98)	<0.001*
Non-AD	452/569 (79.4%)	7,309/7,501 (97.4%)	1		1
Parkinson’s disease
PD	27/569 (4.7%)	25/7,501 (0.3%)	14.90 (8.59–25.84)	<0.001*	4.20 (2.34–7.54)	<0.001*	2.89 (1.56–5.35)	0.001*
Non-PD	542/569 (95.3%)	7,476/7,501 (99.7%)	1		1

AD, Alzheimer’s disease; COVID-19, Coronavirus Disease 2019; PD, Parkinson’s disease.

*Unconditional logistic regression model; significance at p < 0.05.

^†Model 1 was adjusted for age, sex, income, Charlson comorbidity index scores, hypertension and diabetes.

^‡Model 2 was adjusted for model 1 plus Alzheimer’s disease and Parkinson’s disease.