TABLE 4.

Crude and adjusted odds ratios of Alzheimer’s disease and Parkinson’s disease for mortality in COVID-19 participants.

Characteristics	Deceased participants (exposure/total, %)	Surviving participants (exposure/total, %)	Odds ratios (95% confidence interval) for mortality
			Crude	P-value	Model 1†	P-value	Model 2‡	P-value
Alzheimer’s disease
AD	86/237 (36.3%)	223/7,833 (2.8%)	19.44 (14.45–26.14)	<0.001*	2.18 (1.52–3.15)	<0.001*	2.07 (1.42–3.02)	<0.001*
Non-AD	151/237 (63.7%)	7,610/7,833 (97.2%)	1		1		1
Parkinson’s disease
PD	15/237 (6.3%)	37/7,833 (0.5%)	14.25 (7.71–26.34)	<0.001*	2.17 (1.09–4.30)	0.027*	1.54 (0.75–3.16)	0.236
Non-PD	222/237 (93.7%)	7,796/7,833 (99.5%)	1		1		1

AD, Alzheimer’s disease; COVID-19, Coronavirus Disease 2019; PD, Parkinson’s disease.

*Unconditional logistic regression model; significance at p < 0.05.

^†Model 1 was adjusted for age, sex, income, Charlson comorbidity index scores, hypertension and diabetes.

^‡Model 2 was adjusted for model 1 plus Alzheimer’s disease and Parkinson’s disease.