Figure 1.

Leukocyte composition in prednisone and G-CSF GCs. (A) Total leukocyte concentration in prednisone and G-CSF-derived GCs. (B) ANC calculated for a final GC volume of 350 ml. The dashed line indicates the minimal number of neutrophils (10¹⁰) required for granulocyte transfusion. (C) Concentration of leukocyte populations (neutrophils, NE; lymphocytes, LY; monocyte, MO; eosinophils, EO; basophils, BA) in prednisone and G-CSF GCs expressed as cell number per liter. Each dot represents an individual GC donor. Statistical analysis: Mann-Whitney test performed to compare leukocyte concentration and ANC between prednisone and G-CSF GCs: ***p-value < 0.001. Sidak multiple comparisons test performed to compare the concentration of leukocyte populations between prednisone and G-CSF GCs: ****p-value < 0.0001. These data are compiled from the analysis of 9 prednisone and 10 G-CSF GCs.