Table 2.
Composition of donor peripheral blood and granulocyte concentrates.
| Prednisone (n = 9) | G-CSF (n = 10) | |
|---|---|---|
| Donors peripheral blood (pre-collection) | ||
| Total leukocytes (x109/L) (%) | 8.42 | 24.56 |
| Neutrophils | 6.30 (74.8) | 20.55 (83.7) |
| Lymphocytes | 1.52 (18.1) | 2.01 (8.2) |
| Monocytes | 0.49 (5.1) | 1.16 (4.7) |
| Eosinophils | 0.08 (1.0) | 0.49 (2.0) |
| Basophils | 0.03 (0.4) | 0.35 (1.4) |
| Granulocyte concentrate | ||
| Filtrated blood volume (ml) | 4,964 | 4,832 |
| Total leukocyte (x109/L) (%) | 62.85 (100) | 109.45 (100) |
| Neutrophils | 35.70 (56.8) | 82.12 (75.0)** |
| Lymphocytes | 18.29 (29.1) | 17.89 (16.3) |
| Monocytes | 6.59 (10.5) | 7.35 (6.7) |
| Eosinophils | 0.75 (1.2) | 1.58 (1.4) |
| Basophils | 1.52 (2.4) | 0.52 (0.5) |
| Dose ANC/GC unit (x1010) | 1.28 | 2.85 |
| Hemoglobin (g/L) | 34.56 | 22.20** |
| Hematocrit (L/L) | 0.108 | 0.071** |
| Platelets (x109/L) | 297.6 | 261.0 |
ANC, absolute neutrophil count. Comparison of prednisone vs. G-CSF group: t-test,
*
p-value < 0.05;
**
p-value < 0.01.