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. 2022 Mar 19;23:14. doi: 10.1186/s12860-022-00413-w

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — miR-378 was highly expressed in the serum of TB patients and had high diagnostic value. A The expression of miR-378 in the serum of TB patients in the active group and latent group and normal subjects was detected using RT-qPCR; B The diagnostic efficacy of miR-378 in active TB was analyzed using the ROC curve; C The diagnostic efficacy of miR-378 in latent TB was analyzed using the ROC curve; D The diagnostic efficacy of miR-378 in active and latent TB was analyzed using the ROC curve. One-way ANOVA was used for data analysis in panel (A), followed by Tukey's multiple comparisons test, and the ROC curve was used for data analysis in panels B, C, and D. ** P < 0.01. Active TB group (N = 63), latent TB group (N = 63), control group (N = 62). The expression of miR-378 in the control group was normalized to 1. The expression of miR-378 in other groups was relative to that of miR-378 in the control group