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. 2022 Mar 19;23:14. doi: 10.1186/s12860-022-00413-w

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Correlation between miR-378 expression and immune function in TB patients. A The levels of IFN-γ, IL-4, TNF-α, IL-6, IL-12, and IL-1β in TB patients in the active group and latent group and normal subjects were detected using ELISA; Pearson analysis method analyzed the correlation between the expression of miR-378 and (B) IFN-γ, IL-4, TNF-α, IL-6, IL-12, and IL-1β in the serum of patients in the active group and the correlation between the expression of miR-378 and (C) IFN-γ, IL-4, TNF-α, IL-6, IL-12, and IL-1β in the serum of patients in the latent groups. One-way ANOVA was used for data analysis in panel (A), followed by Tukey's multiple comparisons test. * P < 0.05, *** P < 0.001. Pearson coefficient analysis was used for data analysis in panels B and C. Active TB group (N = 63), latent TB group (N = 63), control group (N = 62)