Shown above are the overall release profiles over time for the various drug loaded hydrogels. Novobiocin (top left) showed the least amount of change, where release was statistically comparable, regardless of templating molecule. Vancomycin (top right) showed some change, where release from vancomycin-templated hydrogels was statistically different, particularly in early time points. However release from rifampicin was significantly different depending on whether the hydrogel was templated with the large, hydrophilic VM; the small, moderately hydrophobic NB; or with RM itself (p<0.05). All the hydrogels used were initially imprinted with 9 wt% drug (9% MI). Samples are in triplicate. Error bars show ± standard deviation.