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Veliparib dose proportionality in Groups 1 and 2. (A) Mean (+SD) veliparib Cmax vs veliparib dose. (B) Mean AUC0-7 vs veliparib dose Cycle 1 Day 1. (C) Dose-normalized Cmax Cycle 1 Day 1 vs dose-normalized observed Cmax Cycle 1 Day 3 and Cycle 2 Day 1. (D) Dose normalized AUC0-∞ Cycle 1 Day 1 vs dose-normalized AUC0-12 Cycle 1 Day 3 and dose-normalized AUC Cycle 2 Day 1.
